Isaac Guerendo is a professional football running back and kickoff returner for the San Francisco 49ers, selected in the fourth round of the 2024 NFL Draft after a college career at Wisconsin and Louisville. This tag page collects news, articles, interviews, and updates covering his rookie NFL season, his transition from wide receiver to running back, his role within the 49ers’ backfield alongside Christian McCaffrey and Jordan Mason, and his continued development heading into 2025. The tag is relevant for tracking a young, versatile back whose kickoff return duties, short-yardage usage, and situational carries make him a notable contributor for a team with championship expectations.
